Theragnosis is next-generation healthcare system with therapy and diagnosis. Many researches have been developed for theragnosis using multi-functionalized nanoparticles. However, they showed limitations in-vivo applications because of the size-effect of the particles. Therefore, we have designed small molecules and Nanomaterials with antibacterial properties which provide great advantages such as less cytotoxicity, human-implantation and mass-production. In addition, the small molecules also have a fluorescence in range of NIR that is harmless to human body. The final goal for this project is to create universal theragnosis system for human healthcare.